John Hurt
Dr. Joe Buchanan / Narrator (voice)
Raúl Juliá
Dr. Victor Frankenstein
Nick Brimble
The Monster
Bridget Fonda
Mary Wollstonecraft Godwin
Jason Patric
Lord George Gordon Byron
Michael Hutchence
Percy Byshee Shelley
Catherine Rabett
Elizabeth Lavenza
?
Catherine Corman
Justine Moritz
?
William Geiger
Lab Technician
Mickey Knox
General Reade